Giovanni Gambassi graduated from medical school at the Università Cattolica Sacro Cuore in Rome in 1987; his specialty is internal medicine – geriatrics and cardiology. Currently he holds an academic appointment as Associate Professor in the Dipartimento di Scienze Gerontologiche e Geriatriche. He also serves as the acting-chief of the acute-care geriatric ward in the same Institution. After medical degree, he spent five years (1988-1994) at the National Institutes of Health and Johns Hopkins University contributing seminal work on the molecular regulation of myocardial contractility. Since its inception in 1988, Dr. Gambassi has been a member of the Coordinating Committee of the Gruppo Italiano di Farmacovigilanza (GIFA) Study Group, whose main interest is the study of pharmacoepidemiology in the elderly. In 1995, he was among those responsible of the italian translation of the Resident Assessment Instrument, and since 1996 he has co-ordinated the application of such instrument to many pilot studies in Italy. While appointed as Visiting Professor at Brown University in Providence (1996-1999), Dr. Gambassi established the Systematic Assessment of Geriatric drug use via Epidemiology (SAGE) Study Group. This group has collected an administrative database established as result of the mandatory application of the RAI-MDS in all the Medicare/Medicaid nursing homes in the United States. Dr. Gambassi has been the SAGE scientific co-director ever since and contributed several important studies, in addition to securing a substantial amount of grant funding. Since 1998 he has been named Associate Professor at Brown University and Visiting Professor at the Division of Aging at Harvard Medical school in Boston. Dr. Gambassi is an author of over 150 original publications and numerous review articles, book chapters; he has been an invited speaker in over 200 occasions.